MW: 148,867.07 Da
No. of AA: 1291
Abs 0.1% (g/L): 1.27
pI: 5.46
NCBI ID: CAA37780
UniprotKB: P18640
Strains: phage from 468C botulinum C. strain
Associated Proteins:
Notes:
Nucleotide sequence of Clostridium botulinum C1 neurotoxin.
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The complete nucleotide sequence of the gene coding for botulinum type C1 toxin in the C-ST phage genome.
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Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC-1/syntaxin.
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Botulinum neurotoxin serotype C associates with dual ganglioside receptors to facilitate cell entry.
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Botulinum Neurotoxin Light Chains Expressed by Defective Herpes Simplex Virus Type-1 Vectors Cleave SNARE Proteins and Inhibit CGRP Release in Rat Sensory Neurons.
Joussain C, Le Coz O, Pichugin A, Marconi P, Lim F, Sicurella M, Salonia A, Montorsi F, Wandosell F, Foster K, Giuliano F, Epstein AL, Aranda Muñoz A. (2019). Toxins (Basel)
DOI: 10.3390/toxins11020123 PMID: 30791373