MW: 148,871.06 Da
No. of AA: 1291
Abs 0.1% (g/L): 1.27
pI: 5.46
NCBI ID: BAM65679.1
UniprotKB: P18640
Strains: 468, CB-19, D6F, 7221C, 573, 571c, Davies AO, C-Yoichi, Colworth BL165, 571, IFR 18/084, type C Stockholm, c-st, IZSVe-TV_10018_12, IZSVe-TV_6433_4_13, IZSVe-TV_9877_3_12, Stockholm, IZSVe-TV_6433_3_13, IZSVe-TV_9877_1_12, IZSVe-TV_6537_1_13, IZSVe-TV_6433_6_13, IZSVe-TV_6433_2_13
Associated Proteins:
Notes:
Improved detection methods by genetic and immunological techniques for botulinum C/D and D/C mosaic neurotoxins.
Nakamura K, Kohda T, Seto Y, Mukamoto M, Kozaki S. (2013). Vet. Microbiol.
DOI: 10.1016/j.vetmic.2012.11.009 PMID: 23206412
Characterization of the neurotoxin produced by isolates associated with avian botulism.
Takeda M, Tsukamoto K, Kohda T, Matsui M, Mukamoto M, Kozaki S. (2005). Avian Dis.
DOI: 10.1637/7347-022305R1.1 PMID: 16252491
Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
Zhang S, Berntsson RP, Tepp WH, Tao L, Johnson EA, Stenmark P, Dong M. (2017). Nat Commun
DOI: 10.1038/s41467-017-01534-z PMID: 29158482
Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins.
Schiavo G, Shone CC, Bennett MK, Scheller RH, Montecucco C. (1995). J. Biol. Chem.
DOI: PMID: 7737992
Botulinum neurotoxin C1 cleaves both syntaxin and SNAP-25 in intact and permeabilized chromaffin cells: correlation with its blockade of catecholamine release.
Foran P, Lawrence GW, Shone CC, Foster KA, Dolly JO. (1996). Biochemistry
DOI: PMID: 8611567