MW: 147,247.80 Da
No. of AA: 1277
Abs 0.1% (g/L): 1.314
pI: 5.66
NCBI ID: ADA79559.1
UniprotKB: D2KHQ9
Strains: 2G, SU0632, Af84, BrDura, F634, CDC54085, CDC 54096, CDC 54084, CDC 54074, BrDuraAf, CDC 54075, CDC 54090, CDC 54085, CDC 54079, AF84 (2), IFR 18/081, IFR 16/385
Associated Proteins: BoNT/A2 (CEF8). BoNT/F4 (BD57). BoNT/F4 (E567). NTNH/A2 (CF26). BoNT/A2 (0689).
Notes:
Sequence diversity of genes encoding botulinum neurotoxin type F.
Raphael BH, Choudoir MJ, Luquez C, Fernandez R, Maslanka SE. (2010). Appl Environ Microbiol.
DOI: 10.1128/AEM.03109-09 PMID: 20511432
Clostridium botulinum strain Af84 contains three neurotoxin gene clusters: bont/A2, bont/F4 and bont/F5.
Dover N, Barash JR, Hill KK, Davenport KW, Teshima H, Xie G, Arnon SS. (2013). PLoS ONE
DOI: 10.1371/journal.pone.0061205 PMID: 23637798
Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5.
Kalb SR, Baudys J, Webb RP, Wright P, Smith TJ, Smith LA, Fernández R, Raphael BH, Maslanka SE, Pirkle JL, Barr JR. (2012). FEBS Lett.
DOI: 10.1016/j.febslet.2011.11.033 PMID: 22172278